Search results for "Joint Diseases"

showing 10 items of 23 documents

Correlation of anti-cytoskeleton antibody activities in synovial fluid with interleukin-6 in patients with osteoarthritis and inflammatory joint dise…

1990

Synovial fluids and sera from patients with rheumatoid arthritis, psoriatic arthritis, yersinia arthritis, Behçet's syndrome, Crohn's disease, and osteoarthritis were tested for antinuclear antibodies and antibodies to five cytoskeletal components in sensitive enzyme-linked immunosorbent assay (ELISA) systems and for IL-6 concentrations in a proliferation assay (IL-6 dependent hybridoma cell line B13.29, subclone B9). Statistically significant correlations between antibody activities and IL-6 levels were found for vimentin antibodies (r = 0.56; p less than 0.05) and actin antibodies (r = 0.44; p less than 0.05). In patients with chronic and active disease like rheumatoid arthritis and psori…

AdultMalePathologymedicine.medical_specialtyAnti-nuclear antibodyArthritisEnzyme-Linked Immunosorbent AssayVimentinOsteoarthritisPsoriatic arthritisOsteoarthritisSynovial FluidDrug DiscoveryHumansVimentinMedicineSynovial fluidInterleukin 6Cells CulturedCytoskeletonGenetics (clinical)AgedInflammationbiologyInterleukin-6business.industrySynovial MembraneGeneral MedicineMiddle Agedmedicine.diseaseActinsAntibodies AntinuclearRheumatoid arthritisImmunologybiology.proteinMolecular MedicineFemaleJoint DiseasesbusinessKlinische Wochenschrift
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Risk factors for cystic fibrosis arthropathy: Data from the German cystic fibrosis registry

2021

Epidemiology and potential risk factors for cystic fibrosis arthropathy (CFA) were studied in a relevant cystic fibrosis (CF) patient cohort.Cohort study of patients included in the German CF registry in 2016-2017. Descriptive analysis, exploratory tests and multivariable logistic regression were used to assess prevalence of CFA and associated potential risk factors for adult patients with/without chronic Pseudomonas aeruginosa infection.6069 CF patients aged from 0 to 78 years were analysed. CFA was observed in 4.9% of the patients. Prevalence was significantly higher in adult patients (8.4%) compared to patients18 years (0.7%; p0.0001). Logistic regression analyses in adult patients (n=33…

AdultMalePulmonary and Respiratory Medicinemedicine.medical_specialtyAdolescentCystic FibrosisCystic fibrosis-related diabetesmedicine.disease_causeLogistic regressionCystic fibrosisDiabetes ComplicationsSex FactorsRisk FactorsGermanyInternal medicineArthropathyEpidemiologyPrevalencemedicineHumansPseudomonas InfectionsRegistriesSinusitisChildAgedPseudomonas aeruginosabusiness.industryAge FactorsInfant NewbornInfantMiddle Agedmedicine.diseaseChild PreschoolPediatrics Perinatology and Child HealthCohortExocrine Pancreatic InsufficiencyFemaleJoint DiseasesbusinessCohort studyJournal of Cystic Fibrosis
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Joint involvement in psoriasis.

1974

21 unselected hospital patients with psoriasis (7 female, 14 males) were examined for joint lesions by clinical, roentgenological and scintigraphical methods (6 mCi99mTc-Pertechnetate, 4 mCi99mTc-Pyrophosphate). According to traditional concepts only 5 patients suffered from psoriatic arthropathy, in 8 other patients an extensive case history revealed some joint complaints.

AdultMalemedicine.medical_specialtyAdolescentArthritisDermatologyArthritis RheumatoidDiagnosis DifferentialPsoriatic arthritisPsoriasisArthropathymedicineHumansPsoriasisHospital patientsChildRadionuclide ImagingAgedSacroiliac jointArthritis Infectiousbusiness.industryFootArthritisTechnetiumSacroiliac JointGeneral MedicineMiddle Agedmedicine.diseaseHandDermatologySurgerymedicine.anatomical_structureJoint involvementHalluxFemaleJoint DiseasesbusinessJoint lesionsArchiv fur dermatologische Forschung
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Effects of electrical stimulation on muscle trophism in patients with hemophilic arthropathy.

2009

Abstract Gomis M, Gonzalez L-M, Querol F, Gallach JE, Toca-Herrera J-L. Effects of electrical stimulation on muscle trophism in patients with hemophilic arthropathy. Objective To determine changes occurring in the cross-sectional area, electromyography (EMG) activity, and the strength of the biceps brachii after an 8-week period of bilateral training with surface muscle electrical stimulation in patients with hemophilic arthropathy. Design Controlled trial. Setting Coagulopathy unit, university hospital. Participants Volunteer subjects (N=30) participated in this study: 15 with severe hemophilia A (hemophilic group) and 15 nonhemophilic control subjects (control group). Interventions The he…

AdultMalemedicine.medical_specialtyPhysical Therapy Sports Therapy and RehabilitationStimulationPhysical exerciseElectric Stimulation TherapyIsometric exerciseElectromyographyPhysical strengthHemophilia ABicepsMuscle hypertrophyPhysical medicine and rehabilitationArthropathymedicineHumansMuscle Skeletalmedicine.diagnostic_testbusiness.industryElectromyographyRehabilitationMiddle Agedmedicine.diseaseTreatment OutcomeFemaleJoint DiseasesbusinessArchives of physical medicine and rehabilitation
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Effects of performing dual tasks on postural sway and postural control complexity in people with haemophilic arthropathy

2019

Introduction People with haemophilic arthropathy (PWHA) have impairments in postural control. However, little is known about the effects of demanding conditions, including the unipedal stance and dual tasks, on postural control in PWHA. Aim Determine the effects of performing dual tasks while in the one-leg stance on postural sway and postural control complexity in PWHA vs. healthy active (HAG) and non-active (HNAG) groups of individuals. Methods Fifteen PWHA and 34 healthy subjects (18 active and 16 non-active) were recruited. Vertical (V), mediolateral (ML) and anteroposterior (AP) centre of mass signals were acquired using a 3-axis accelerometer placed at the L3/L4 vertebrae of subjects …

AdultMalemedicine.medical_specialtyPoison control030204 cardiovascular system & hematologyHemophilia APostural controlYoung Adult03 medical and health sciences0302 clinical medicinePhysical medicine and rehabilitationmedicineHumansPostural BalanceGenetics (clinical)Balance (ability)Haemophilic arthropathybusiness.industryHealthy subjectsMotor controlHematologyGeneral MedicineSample entropyCase-Control StudiesHealthy individualsFemaleJoint Diseasesbusiness030215 immunologyHaemophilia
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The relationship between functional disability and health-related quality of life in patients with a rotator cuff tear

2012

To determine the relationship between functional disability and health-related quality of life (HRQoL) in rotator cuff tear (RCT) patients.In 67 RCT patients (mean age, 54 years; 57% males), functional disability was self-reported with the American Shoulder and Elbow Surgeons Standardized Shoulder Assessment Form (ASES), HRQoL with the Short-Form 36 Health Survey (SF-36), and pain by visual analogue scale. ASES results were divided into tertiles (12-38, 39-51, and 52-82).Mean ASES score was 48 (range, 12-82). Patients with the highest functional disability and highest pain level had the lowest HRQoL. For the highest, middle, and lowest ASES categories, respectively, mean SF-36 Physical Comp…

AdultMalemedicine.medical_specialtyanimal structuresPatientsVisual analogue scaleHealth StatusElbowRotator Cuff Injurieslaw.inventionDisability EvaluationRotator CuffQuality of lifeRandomized controlled triallawSurveys and QuestionnairesHumansMedicineRotator cuffIn patientRange of Motion ArticularArthrographyPain MeasurementRuptureHealth related quality of lifeShoulder Jointbusiness.industryRehabilitationta3141Recovery of FunctionMiddle AgedHealth SurveysMagnetic Resonance ImagingTreatment Outcomemedicine.anatomical_structureFunctional disabilityQuality of LifePhysical therapyFemaleJoint DiseasesbusinessDISABILITY AND REHABILITATION
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Neuromuscular control during gait in people with haemophilic arthropathy

2019

Introduction: Effects of haemophilic arthropathy on neuromuscular control during gait are currently unknown. Aims: (a) To assess how haemophilic arthropathy affects the complexity of neuromuscular control during gait; (b) To investigate the relationship between complexity of neuromuscular control and joint impairment. Methods: Thirteen control subjects (CG) walked overground at their preferred and a slow velocity and thirteen people with haemophilic arthropathy (PWHA) walking at their preferred velocity. Surface electromyography (EMG) was collected from eleven leg muscles. Electromyography variance explained by muscle synergies (sets of co-activated muscles that can be recruited by a single…

AdultMalemedicine.medical_specialtyhaemophiliaElectromyographyWalking030204 cardiovascular system & hematologyKnee Jointsurface electromyographyHaemophiliaHemophilia AHemophilia BSeverity of Illness Indexknee joint03 medical and health sciencesYoung Adult0302 clinical medicinePhysical medicine and rehabilitationSDG 3 - Good Health and Well-beingneuromuscular controlmedicineCluster AnalysisHumansankle jointMuscle SkeletalGaitGenetics (clinical)medicine.diagnostic_testbusiness.industryElectromyographymuscle synergyMotor controlHematologyGeneral MedicineExplained variationmedicine.diseaseGaitmedicine.anatomical_structureCase-Control Studies/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingAnkleNeuromuscular controlJoint Diseasesbusinesshuman activities030215 immunology
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A case of lipogranulomatosis Farber: some clinical and ultrastructural aspects

1985

A 20-month-old girl showed typical clinical signs of Farber disease: hoarseness since birth, and periarticular subcutaneous painful nodules. Complete deficiency of acid ceramidase activity was found in cultured skin fibroblasts. An electron microscopic examination of a dermal nodule disclosed pathognomonic tubular inclusions in histiocytes. In epidermal cells zebra-body-like and needle-like lysosomal inclusions were found. Their ultrastructure is different from that of the intrahistiocytic lysosomal inclusions. Probably three clinical types of Farber disease may be distinguished according to the symptomatology and the course of the disease: a severe type, an intermediate type and a relative…

AdultPathologymedicine.medical_specialtyAcid CeramidaseAmidohydrolasesPathognomonicArthropathyCeramidasesmedicineHumansLipomatosisLymphocytesHistiocyteSkinFarber diseaseGranulomaHoarsenessbusiness.industryClinical coursemedicine.diseaseIntermediate typeAcid CeramidasePediatrics Perinatology and Child HealthUltrastructureFemaleJoint DiseasesbusinessEuropean Journal of Pediatrics
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Effect of radiosynoviorthesis on the progression of arthropathy and haemarthrosis reduction in haemophilic patients.

2017

IntroductionRepeated haemarthrosis is widely accepted as the triggering cause of synovitis and haemophilic arthropathy. A first-line treatment of chronic synovitis is radiosynoviorthesis (RS). The aim of this study was to evaluate the RS effects on the progression of arthropathy and on a reduction in bleeding in patients with haemophilia. MethodsAn observational-retrospective study was performed. Bleeding episodes in the 12months following and in the 12months preceding RS was compared. The arthropathy was clinically and radiologically analysed by age range, joint and subject, comparing those undergoing RS (Radiosynoviorthesis Group, RSG) against those not undergoing this treatment (Non-Radi…

Adultmedicine.medical_specialtyAdolescentmedicine.medical_treatment030204 cardiovascular system & hematologyHaemophiliaHemophilia AGastroenterologyradiosynoviorthesis03 medical and health sciencesYoung Adult0302 clinical medicinehaemarthrosisSynovectomyInternal medicineSynovitisArthropathyElbow JointHemarthrosismedicineHumansIn patientYttrium RadioisotopesGenetics (clinical)Reduction (orthopedic surgery)Retrospective StudiesRadioisotopesHaemophilic arthropathyBleeding episodesSynovitisbusiness.industryShoulder Jointhaemophilic arthropathyHematologyGeneral MedicineMiddle Agedmedicine.diseaseChronic synovitisRheniumTreatment OutcomeDisease ProgressionJoint DiseasesbusinesssynovitisAnkle Joint030215 immunologyHaemophilia : the official journal of the World Federation of Hemophilia
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Comparison of the rates of joint arthroplasty in patients with severe factor VIII and IX deficiency: an index of different clinical severity of the 2…

2009

AbstractData from the Italian Hemophilia Centres were collected to perform a retrospective survey of joint arthroplasty in patients with severe hemophilia. Twenty-nine of 49 hemophilia centers reported that 328 of the 347 operations were carried out in 253 patients with severe hemophilia A (HA) and 19 in 15 patients with severe hemophilia B (HB). When results were normalized to the whole Italian hemophilia population (1770 severe HA and 319 severe HB), patients with HA had a 3-fold higher risk of undergoing joint arthroplasty (odds ratio [OR], 3.38; 95% confidence interval [CI], 1.97-5.77; P < .001). These results were confirmed after adjustment for age, HIV, hepatitis C virus (HCV), and…

Adultmedicine.medical_specialtyAdolescentmedicine.medical_treatmentImmunologyPopulationmacromolecular substancesGene mutationHemophilia AHemophilia BSeverity of Illness IndexBiochemistryArthroplastySettore MED/15 - Malattie Del SangueCohort StudiesYoung AdultRisk Factorshemic and lymphatic diseasesInternal medicineSeverity of illnessmedicineCoagulopathyHumansChildeducationRetrospective Studieseducation.field_of_studyHematologyhamophilia arthroplastybusiness.industryRetrospective cohort studyCell BiologyHematologyOdds ratioBlood Coagulation DisordersMiddle Agedmedicine.diseaseArthroplastySurgeryItalyJoint DiseasesbusinessAlgorithms
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